Well one this is in the wrong forum.. but regardless..
When you say the file becomes "invalid" what exactly do you mean by that? Do you get some sort of error message? Is the drawing gone? etc?
people will be in a drawing working and it will go read only when it happens.
I can't say that I've ever seen a drawing go to read-only while it's currently open and I work solely off of a networked file server. Is this Autocad or a different Autodesk product since I'm only familiar with Autocad, I thought it only checks read-only status when it's opening and if the file gets opened in read-only it won't change to a full access unless reopened.
That said I don't think your phone system would be causing problems like that. It's more likely that an antivirus app on the server is messing with the temp files while you are working. Even that might be a stretch.
To me is seems that the switches aren’t configured correctly
Ideally the traffic should be completely segregated by VLAN's. You really don't want your traffic mixing in your lan more for the sake of the SIP traffic's QOS than the standard lan traffic. But that's not required, just recommended. Alot of it depends on the size of your network, hardware, # of users etc. It's hard to say more without capturing traffic data and looking at it. Your vendor that sold you the CISCO stuff should have done that previous to installation.