TitleBlock/Border is in paperspace....
all else in modelspace (drawn 1:1), with scaled viewport(s) in paperspace, and printed from paperspace.
All is well-organized and labeled (on non-printable layers, of course) in modelspace for easy reference, as well.
With a variety of clients, this works best for everyone. I even occasionally detail for a fabricator who prints out TO SCALE from modelspace -- he's got someone who prints on [unspecified] extra L.A.R.G.E. media for him -- so his guys in the shop have a template for stair stringers and other miscellaneous steel items! Crazy, huh?