Is anyone out there using Sheet Set Manager to do their plotting? You can either have the drawings plot using the default page setup or select a page setup override. For instance; Let's say your default page setup plots to a PLT file. You can have multiple page setup overrides that would send the drawings to an 11x17 sheet (scaled down), a PDF file, or anything else you want to set up. I've found that to be MUCH easier than using the straight PUBLISH command.
In the image below, I can quickly create PLTs for 79 files with a simple click of the mouse using the default page setup.