First let me say I don't use Autocad or any of AD's products so take this FWIW...
Once you use two monitors you will never go back. The program I use for residential (Softplan) has another program (or module depending on how you think of it) that takes care of the 3d views and rendering. So as I am laying out and drafting the floor plan on one monitor I can see the effects on the 3d model in the other monitor. This works great for window/door placement, wall and header hts., etc. And if I'm not doing that then I can have my email open in one monitor and whatever else open in the other. Pretty dang awesome. I am getting greedy and thinking about going with 3 soon.
I run 2 19" lcds BTW. Not that they are cheap but they are alot less expensive than they were and the savings in desk area is huge. At least for me.
I just got a new setup here about a month ago. A Dell with the pentium D 930 dual core. It is fast but the only place I really see a remarkable improvement is in the 3d rendering. The new version of Softplan that was just released a couple months ago takes advantage of the dual chip processors. (I'm not a techy I just read alot) So for instance one chip is running softplan (as I draw the floor plan) and the other chip is running softview (the 3d module I talked about earlier) which of course makes the generation of the 3d views much faster. I will say though that everything I read about dual processors leaned much more towards AMDs for everything except 3d rendering. For whatever reason it was better for that. Which I do alot of so this was the way I went.
I have no clue about AD products but in Softplan all the 3d (again from what I've read) is much more reliant on processor than video card. Even the renderings. The only advantages of having an awesome video card are for 3d model animations (walk throughs or panoramas of the model). Otherwise it's best to put the money in the processor.
This is probably the longest semi-coherent post I've ever had here. Woot!