I'm thinking about upgrading my mouse at work.
I currently use a Micro$oft Intellimouse, the infrared one with 4 buttons (not counting the wheel button) and I have the thumb button programmed as ESC and the other one as F8. I have the wheel button set as F3 and couldn't imagine doing CAD with anything less.
I've looked at the nostromo thinger, they have an older model available at Big Lots out here for less than 10 bucks but I'm not convinced that I'll like it. Then again, I wasn't convinced I'd like the 4/5 button mouse either. It took me a while to get used to using a mouse after using a SummaSketch tablet for years (still have 4 or 5 of the tablets sitting here in my garage) so I dunno... it's only 10 bucks. If I don't like it I can always turn it into a borg hand thinger for next years halloween costume