I have a small VB.NET project which finds some drawing files on our LAN and lists them in a ListBox. The user can simply click on the item in the list box and it uses Process.Start to open it up in AutoCAD. In the past, this worked great and used an existing instance of AutoCAD automatically. That is if the user already has AutoCAD open and they click on the file in the ListBox, it just opens up a new drawing in that existing instance of AutoCAD. If not, it opens up a new instance of AutoCAD. My computer, however, opens up a new instance of AutoCAD each and every time I do this. So far, my computer is the only one in this department that's doing this.