Yes, and due to reactors only working if they're loaded - these "unscalable" blocks will only be unscalable on the workstations where you installed the reactor. Every other PC / ACad install will still be able to scale them without any issue.
The closest you can get is to make the block annotative, though that's more like the opposite of unscalable -> more like automatically scaled.
Unfortunately these sort of things only work if ADesk adds the feature into the acad program itself so that everyone's acad works the same way. And even then older versions or clones like BricsCAD would not adhere to this setting (most probably).
Edit: Just a query ... what are you actually after? Might it be useful to place the blocks on a locked layer?