I use AMEP 10 hours a day every day. Custard is 100% correct in his description regarding the Plumbing workspace. The Piping workspace has everything you need for plumbing and piping, and it's all 3D. Right now I'm working on a huge $15 million dollar project and it has steam pipe (which is sloped), steam condensate, chemical pipe, copper pipe, plastic PVC, grooved piping, threaded steel pipe, stainless socket weld pipe, stainless butt-weld pipe, and more just on this one project. Right out of the box, AMEP has everything I have thrown at it as far as all the different types of piping material and connection/routing preferences. Pretty impressive actually.
I also compared the stock catalog of fittings with the manufacturers we're using and the dimensions are dead-on accurate, I'm assuming from ANSI standards. Even if they aren't, they're easily editable.
Sloped piping on AMEP works amazingly well, actually. There was definitely a learning curve to understand how AMEP wants you to input and route the pipe but once you wrap your mind around how it likes to be told what to do, it's a breeze drawing sloped piping.