Is this question asked to help figure out how this property would be surveyed?
What monuments were found? Are any of them mentioned in any recorded documents?
Other than that the road should get it's width first, then the distances prorated into the blocks.
I'd have to review some Florida law and history (I'm not licensed in FL) but here in VA I'd almost consider lot 80 as being a remainder lot, reason being in 1925 depending on the surveyor the math may not have been worked. It could be a guess, however at the same time he's given the distance to the hundredth of a foot so I'm a little skeptical of that. However it could also be likely that the "68.25" is the chord distance from corner of 79/80 to the corner of 81/80, reason being that it was an easier calculation to make in 1925.
At the very least I'd look for corners on the three blocks that form this intersection.