Sure. In the treeview on the left, traverse down to "Runtime Security Policy." Then, in the right-hand pane, click the link labeled "Adjust Zone Security." You will be asked if you want the changes to apply to the machine or only the local user. Choose whichever is appropriate for you, and click "Next." Select "Local Intranet" on the dialog that appears next, and bump the trust level up until your program works. Note, there may be good reasons for keeping the trust level low for the local intranet zone, so think carefully about how important it is that you be able to run your program from the network.
Good luck.