Well, lets see ...
You mentioned scaling the drawing
this has its advantages, it is quick and painless
and its disadvantages, the linetype scales for items are screwed up
So, the bottom line is that to utilize this way, you will need to physically change the linetype scale of each entity. This is fine except that blocks will have to be refedited and will be difficult to manage.
Another option is to simply change the dimension scaling, but you will then need to draw everything 1/25.4 of the actual size.
I dunno .. a lisp could work wonders, changing the items in the properties dialog would work ...