string appPath = Directory.GetCurrentDirectory();
appPath = appPath.Replace(@"\", @"/");
string my_cmd = "(load " + Convert.ToChar(34) + appPath + "/Tci2.lsp" + "" + Convert.ToChar(34) + ") ";
acDoc.Editor.Command(my_cmd + "\r");
acDoc.Editor.Command("Tci2" + "\r");
But with plain .NET you can call LISP function using the Application.Invoke() method.as in the above code.