If your computer is managed by a Microsoft Exchange administrator or a Microsoft Windows Active Directory Domain Services administrator in your organization, and the administrator changes the default setting and prevents users from making changes, the option to customize the Programmatic Access security settings will be disabled.
If your computer is not managed by an Exchange administrator or a Microsoft Windows Active Directory Domain Services administrator, and you are the Windows administrator of your computer, you can change the Programmatic Access security settings. However, this is not recommended.
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