JayRem
You have not indicated how you do it exactly. Also you have not defined any parameters.
Like:
Can the 8 foot side of the panel be horizontal and / or vertical?
Can you break the pattern at floor levels or some vertical point?
Do the 4 foot sides have to be staggered?
Is there a structural or aesthetic requirement to the placement?
Are expansion joints going to be used?
Does the material recovered from an opening have to be a minimum size before it can be reused?
Do you have to start at one side or bottom with full size panels?
That is just off the top of my head, I would have to ponder the problem awhile to complete
the list of questions?
So you see your question is too vague for an answer.
Even with all these options known the problem is complex and would have to have some priority
to the method used. That is unless the only criterion is the minimum waste.
My thought is that the solution is too complex for someone to invest the time without some incentive.
My 2 cents.